It is hypothesized that there are fluctuations in norepinephrine (NE) levels which accompany fluctuations in affect with bipolar affective disorder (manic-depressive illness). Thus, during depressive states, NE levels drop; during manic states, NE levels increase. To test this relationship, researchers measured the level of NE by measuring the metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG in micro gram per 24 hour) in the patient’s urine experiencing varying levels of mania/depression. Increased levels of MHPG are correlated with increased metabolism (thus higher levels) of central nervous system NE. Levels of mania/depression were also recorded on a scale with a low score indicating increased mania and a high score increased depression. The data is provided below.
Affect
Compute the correlation coefficient.
What does this statistic mean concerning the relationship between MHPG levels and affect?
What percent of the variability is accounted for by the relationship between the two variables?
What would be the slope and y-intercept for a regression line based on this data?
What would be the predicted affect score if the individual had an MHPG level of 1100? of 950? of 700?
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