describe the symptoms associated with Alzheimers, discuss the the role of neurofibrillary tangles and amyloid plagues, in the development of the disease and highlight regions of the brain most affected by this disease

describe the symptoms associated with Alzheimers, discuss the the role of neurofibrillary tangles and amyloid plagues, in the development of the disease and highlight regions of the brain most affected by this disease

Whitehouse, P., D. Price, R. Struble, A. Clark, J. Coyle, and M. Delon. “Alzheimer’s Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain.” Science 215.4537 (1982): 1237-239.

Tatsch, Mariana Franciosi, Cássio Machado De Campos Bottino, DionísioAzevedo, Sérgio Ricardo Hototian, Marco AntônioMoscoso, Jefferson Cunha Folquitto, AndréiaZavaloneScalco, and Mario Rodrigues Louzã. “Neuropsychiatric Symptoms in Alzheimer Disease and Cognitively Impaired, Nondemented Elderly From a Community-Based Sample in Brazil: Prevalence and Relationship With Dementia Severity.” American Journal of Geriatric Psychiatry 14.5 (2006): 438-45.

Lecrux, C., and E. Hamel. “The Neurovascular Unit in Brain Function and Disease.” ActaPhysiologica 203.1 (2011): 47-59
I. Definition and incidence of Alzheimer’s?
a. Discovery of Alzheimer’s?
b. Relation to dementia?
c.Characteristics of the disease
II. Progression of Alzheimer’s?
a. Description of 4 stages
b. Neurofibrillary tangles and amyloid plagues
c. Nerve cell death and tissue loss
III. Causes/risk factors of Alzheimer’s
a. Age?
c. Head trauma (close head traumas)
d. Family history?
e. Other factors
IV. Diagnosis of Alzheimer’s?
a. Neurological examination?
b. Postmortem examination
V. Treatment of Alzheimer’s?
a. Drugs?
b. Therapies
VI. Conclusion