Maturation processes within developmental stages in the foetus

After birth, the foetus is required to adapt to the environmental changes by establishing and maintaining physiological homeostasis, without the assistance of the placenta. Therefore, the survival of the foetus after birth is dependent upon maturation of structures and organs that interface with the new environment. Examples of essential organs and structures are lungs, immune system, gut, liver, pancreases and kidney (Strauss & ‎Barbieri, 2013). Various studies have shown that maturation processes during foetal development are induced by glucocorticoids (Strauss & ‎Barbieri, 2013). Critical maturation processes that occur during foetal development include deposition of glycogen in the liver; activity of enzyme systems in the foetal brain, thyroid gland, pancreases, retina, and gut; and production of surfactant by foetal lungs. Maturation of the foetal lungs is particularly important since inability to breathe due pulmonary immaturity has been found to be a leading cause of mortality among preterm infants as well as neonatal morbidity (Norris & Lopez, 2010). However, the key functions of glucocorticoids in the process of maturation are not yet clear. As Norris and Lopez (2010) highlight, some studies have shown that glucocorticoids do not initiate maturation of cells; they simply accelerate the process of maturation.