Sequencing several genomes, including that of the zebra fish, has revealed a number of receptors and transporters. In one case, positional cloning of the zebra fish golden gene identified a putative cation exchange protein called SLC24A5. When the golden gene is mutated, the normally black horizontal stripes are pale or golden in appearance because the amount of black pigment or melanin is greatly reduced. Design an experiment to identify where the protein encoded by the golden gene is expressed and localized in the zebra fish. What is the term used when a mutant gene and its phenotype, for instance golden in zebra fish, is rescued by expressing an orthologous gene from another animal?
Define the orthologous gene and golden gene
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