Write an introductory passage discussing the disease your choice is used to treat and including consideration of the health and/or social impacts of the disease and why there was considered to be an un-met need for this new drug. Show how the pharmacological target was selected and discuss why it was believed to be involved in the pathophysiology of the disease and how this has been supported. Discuss the design of the drug molecule from initial chemical leads. Describe the pharmacological properties of the drug molecule itself and explain how it fulfilled the requirements of a clinical candidate. Include a summary of what clinical studies have been presented in support of using the drug clinically.
Discuss the design of the drug molecule from initial chemical leads.
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