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The Trouble with Vision Pedigree

A woman by the name of Stella Hansen had an eye condition that none of the other women in her family had. She married a man called Alfred Jones who did not have the eye condition. They had six children, Samantha, Carrie, Teresa, Randall, Herbert and David. All three boys had the eye condition but none of the girls displayed this eye condition. Samantha married John who did not have the eye condition and they had three sons Ben, Jerome and William. Ben and William both had the eye condition but Jerome did not.

Draw a pedigree using squares and circles and darken in all the affected individuals. Use Roman numerals for the generations and use the names to show individuals in the pedigree. Make a representation of this family using a pedigree drawn freehand on paper or use the computer. Make sure you provide a key to represent male, female and affected male or female with your pedigree drawing. After you finish your drawing ask your instructor to check it. Answer the questions below.

1. Is this condition recessive or dominant? Explain why you think your answer is correct.

1. What is the genotype of Stella Hansen for the eye condition?

1. Could this condition be a sex-linked trait? Explain why you think it is or isn’t.

1. What genotype do you think Samantha might be for this eye condition?

1. From the information given are there any other people in this pedigree that you can guess their genotype? Write the genotypes of all the people you believe there is sufficient information.

1. Is there any member in this pedigree that you believe you do not have enough information on to guess their genotype? Who are they?

1. Do you know what kind of trait this vision condition is? What is it?

Webbed Toed Wonders

A family has an unusual trait having webbing to the tips of their toes in affected family members. The grandmother had this condition but the grandfather did not. There were six children in the second-generation–three boys Philip, Paul and Samuel and three girls Jessica, Jenny and Joan. Three of the children had webbed toes–Paul, Samuel and Joan. Philip, Jessica and Jenny did not have webbed toes. Paul married and also had six children Joseph, Jacob, Joshua, Jane, Sandy and Nicole. Paul’s wife does not have webbed toes, neither do any of his three sons. However, all three of Paul’s daughters have webbed toes.

Draw a pedigree using squares and circles and darken in all the affected individuals. Use Roman numerals for the generations and use the names to show individuals in the pedigree. Get an additional sheet of paper or use the backside of the vision pedigree. Then, draw a representation of the family using a pedigree. Make sure you provide a key to represent male, female and affected male or female with your drawing.After you complete your pedigree and your instructor checks it, answer the questions below.

1. Can you determine whether this condition for webbed toes is dominant or recessive? Explain your answer.

1. Can you determine whether this trait is sex-linked by the information given? Explain why or why not.

1. If webbed toes are sex-linked does it make sense that all of Paul’s daughters would have webbed toes and none of his sons? Explain your answer.

1. Can you determine the genotype of the grandmother because two sons and a daughter had the condition and two daughters and one son does not? Explain your answer.

1. If Paul had the gene for webbed toes of his X-sex chromosome would any of his sons be able to inherit this condition from him? Explain your answer and provide a Punnett square.

1. Can the condition for webbed toes be recessive if it is a sex-linked trait on the X-sex-chromosome? Explain your answer.

1. Is it possible that the condition for webbed toes is on another set of chromosomes other than the sex chromosomes? Explain your answer.